Ribostamycin Sulfate

硫酸核糖霉素 (Vistamycin sulfate) 是一种广谱抗菌剂，在 30S 和 50S 核糖体亚基结合水平抑制细菌蛋白质合成，还抑制蛋白质二硫键异构酶 (PDI) 的伴侣活性，用于药代动力学和肾毒性研究

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5g

￥250.00

200.00

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25g

￥950.00

760.00

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Background

Ribostamycin is a broad-spectrum antimicrobial, inhibits bacterial protein synthesis at the level of 30S and 50S ribosomal subunit binding, also inhibits the chaperone activity of protein disulfide isomerase (PDI), used in pharmacokinetic and nephrotoxicity studies

参考文献:
[1]. Baud H, et al. Ribostamycin, as an intermediate in the biosynthesis of neomycin. J Antibiot (Tokyo). 1977 Sep;30(9):720-3.
[2]. Hunfeld KP, et al. In vitro activity of mezlocillin, meropenem, aztreonam, vancomycin, teicoplanin, ribostamycin and fusidic acid against Borrelia burgdorferi. Int J Antimicrob Agents. 2001 Mar;17(3):203-8.
[3]. Horibe T, et al. Ribostamycin inhibits the chaperone activity of protein disulfide isomerase. Biochem Biophys Res Commun. 2001 Dec 21;289(5):967-72.