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  • (±)-Jasmonic Acid methyl ester
(±)-Jasmonic Acid methyl ester的可视化放大

(±)-Jasmonic Acid methyl ester

A plant growth regulator

原价
¥550-2087
价格
440-1670
(±)-Jasmonic Acid methyl ester的二维码

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  • 货号: ajci16992
  • CAS: 39924-52-2
  • 别名: 甲基茉莉酮酸酯,(±)-Methyl Jasmonate
  • 分子式: C13H20O3
  • 分子量: 224.3
  • 纯度: >98%
  • 溶解度: ≤30mg/ml in ethanol;15mg/ml in DMSO;25mg/ml in dimethyl formamide
  • 储存: Store at RT
  • 库存: 现货

Background

(±)-Jasmonic Acid methyl ester can suppress proliferation and induce apoptosis.


Jasmonates, a group of plant stress hormones that naturally occur in plants following exposure to certain types of stresses, includ pathogen and herbivore attacks.


In vitro: It was found that (±)-Jasmonic Acid methyl ester, when applied to surfaces of tomato plants, could induce the synthesis of defensive proteinase inhibitor proteins. The presence of (±)-Jasmonic Acid methyl ester in the chamber atmosphere containing plants resulted in the accumulation of proteinase inhibitors in leaves of all studied three species [1]. Another study found that (±)-Jasmonic Acid methyl ester could induce death in each of the studied cell lines, while other plant stress hormones could not affect normal human lymphocytes. In addition, (±)-Jasmonic Acid methyl ester caused apoptotic death, as measured by flow cytometric DNA profile, characteristic nuclear morphology, and caspase-3 activity elevation [2].


In vivo: Animal study showed that mice bearing EL-4 lymphoma and treated with (±)-Jasmonic Acid methyl ester survived for significantly longer periods of time than untreated mice, suggesting that plant stress hormones might potentially be a new class of anti-cancer drugs [2].


Clinical trial: So far, no clinical study has been conducted.

参考文献:
1.? Farmer, E.E. and Ryan, C.A. Interplant communication: Airborne methyl jasmonate induces synthesis of proteinase inhibitors in plant leaves. Proceedings of the National Academy of Sciences of the United States of America 87, 7713-7716 (1990).
2.? Fingrut, O. and Flescher, E. Plant stress hormones suppress the proliferation and induce apoptosis in human cancer cells. Leukemia 16, 608-616 (2002).

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