9-cis Retinal

A natural retinoid

原价

￥825-4425

价格

￥ 660-3540

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库存: 现货

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产品引用

货号: ajci21020
CAS: 514-85-2
别名: 9-顺式视黄醛
分子式: C20H28O
分子量: 284.4
纯度: >98%
溶解度: DMF: 25 mg/ml,DMSO: 16 mg/ml,Ethanol: 25 mg/ml,Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
储存: Store at -20°C,protect from light
库存: 现货

Background

9-cis Retinal is a natural retinoid that is produced by oxidation of 9-cis retinol by cis-retinol dehydrogenase (cRDH). It binds to cellular retinol-binding protein-I (CRBP-I) and CRBP-II (Kds = 8 and 5 nM, respectively) and to cellular retinaldehyde-binding protein (CRALBP; Kd = 53.3 nM). In vitro, 9-cis retinal inhibits differentiation of RCJ C5.18 chondrogenic cells into cartilage (IC50 = 8 nM). In vivo, it rescues cone electroretinogram (ERG) responses in Irbp-/- mice, which lack interphotoreceptor retinoid-binding protein and have diminished cone responses, when administered at a dose of 0.375 mg.

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信号通路

生命科学

有机化学

无机化学

材料科学

9-cis Retinal

9-cis Retinal详情

Background