现货大促销，价格低至8折起，量大更优惠，详细咨询客服
安捷凯生物医药，安捷凯化学
全部分类
全部分类
  1. 首页
  2. Cyclooxygenase (COX)
  3. CAY10452
  • CAY10452
CAY10452的可视化放大

CAY10452

A non-apoptotic, selective COX-2 inhibitor

原价
￥337-2725
价格
￥ 270-2180
CAY10452的二维码

所有产品仅用于科学研究，我们不为任何个人用途提供产品和服务

询价有惊喜，量大更优惠 点击这里给我发消息

  • 库存: 现货
可选包装 >>>
首页
  • 货号: ajci21096
  • CAS: 170569-87-6
  • 别名: 塞来昔布杂质3
  • 分子式: C16H12F3N3O2S
  • 分子量: 367.3
  • 纯度: >98%
  • 溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2)(1:8): .1 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Inhibitors of cyclooxygenase (COX) are generally grouped according to selectivity for COX-1 versus COX-2. However, many COX inhibitors also show an antitumor, pro-apoptotic activity that is distinct from COX inhibition - celecoxib is an example. CAY10452 is a celecoxib analog that retains potent, selective COX-2 inhibitory activity (IC50 = 32 nM), but does not induce apoptosis in prostate cancer cell lines even at 100 uM. CAY10452 is thus a clean, selective tool for the inhibition of COX-2.

动态评分

0.0

没有评分数据
没有评价数据
一键回到顶部
展开 收缩
安捷凯在线客服