Cardanol monoene

An inhibitor of tyrosinase with anticancer properties

原价

￥762-10887

价格

￥ 610-8710

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产品引用

货号: ajci21140
CAS: 501-26-8
别名: 腰果酚(C15:1),Cardanol C15
分子式: C21H34O
分子量: 302.5
纯度: >98%
溶解度: DMF: 20 mg/ml,DMSO: 15 mg/ml,Ethanol: 22 mg/ml,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
储存: Store at -20°C
库存: 现货

Background

Cardanol monoene is a phenol found in cashew nut shell liquid that reversibly inhibits tyrosinase with an IC50 value of 56 uM in vitro. It halts the cell cycle at the S phase and inhibits proliferation dose- and time-dependently in M14 melanoma cells (IC50s = 23.15 and 12.30 uM after 24 and 48 hours of treatment, respectively). Cardanol monoene also induces apoptosis via the intrinsic pathway following the accumulation of reactive oxygen species (ROS). A mixture of cardanol mono-, di-, and triene is used to synthesize cardanol-metal complexes that inhibit uropathogenic E. coli biofilm formation.

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生命科学

有机化学

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材料科学

Cardanol monoene

Cardanol monoene详情

Background