现货大促销,价格低至8折起,量大更优惠,详细咨询客服
全部分类
全部分类
  • 4α-Phorbol 12-myristate 13-acetate
4α-Phorbol 12-myristate 13-acetate的可视化放大

4α-Phorbol 12-myristate 13-acetate

A negative control for PMA

原价
¥1212-1212
价格
970-970
4α-Phorbol 12-myristate 13-acetate的二维码

所有产品仅用于科学研究,我们不为任何个人用途提供产品和服务

询价有惊喜,量大更优惠 点击这里给我发消息

  • 库存: 现货
可选包装 >>>
首页
  • 货号: ajci21312
  • CAS: 63597-44-4
  • 别名: 4ALPHA-12-O-十四碳酰基佛波醇13-乙酸酯,α-TPA
  • 分子式: C36H56O8
  • 分子量: 616.8
  • 纯度: >98%
  • 溶解度: DMSO: Soluble,Ethanol: Soluble,Methanol: Soluble
  • 储存: Store at -20°C;protect from light
  • 库存: 现货

Background

Phorbol 12-myristate 13-acetate is a phorbol ester that is commonly used to activate certain types of PKC, including group A (α, βI, βII, γ) and group B (δ, ε, η, θ) isoforms. 4α-PMA is a structural analog of PMA that does not activate PKC. It is used as a negative control for PMA signaling through PKC.


参考文献:
[1]. Blumberg, P.M. Protein kinase C as the receptor for the phorbol ester tumor promoters: Sixth Rhoads Memorial Award Lecture Cancer Research 48(1), 1-8 (1988).
[2]. Fischer, S.M., Patrick, K.E., Lee, M.L., et al. 4β- and 4α-12-O-tetradecanoylphorbol-13-acetate elicit arachidonate release from epidermal cells through different mechanisms Cancer Res. 51(3), 850-856 (1991).
[3]. Savage, M.J., Trusko, S.P., Howland, D.S., et al. Turnover of amyloid β-protein in mouse brain and acute reduction of its level by phorbol ester Journal of Neuroscience 18(5), 1743-1752 (1998).

动态评分

0.0

没有评分数据
没有评价数据
一键回到顶部
展开 收缩
安捷凯在线客服