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  2. PKC (Protein kinase C)
  3. Bisindolylmaleimide III
  • Bisindolylmaleimide III
Bisindolylmaleimide III的可视化放大

Bisindolylmaleimide III

A PKC inhibitor

原价
￥962-2912
价格
￥ 770-2330
Bisindolylmaleimide III的二维码

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  • 库存: 现货
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  • 货号: ajci21418
  • CAS: 137592-43-9
  • 别名: BIM III
  • 分子式: C23H20N4O2
  • 分子量: 384.4
  • 纯度: >98%
  • 溶解度: DMSO: soluble,Methanol: soluble
  • 储存: Store at -20°C
  • 库存: 现货

Background

Bisindolylmaleimide III was developed as a protein kinase C (PKC) inhibitor with structural similarity to the nonspecific PKC inhibitor staurosporine. At 1 μM, bisindolylmaleimide III inhibits 93% of PKCα kinase activity and also inhibits many other protein kinases including, S6K1, MAPKAP-K1, RSK2 and MSK1 with similar potency. Additionally, it inhibits PDK1, an important kinase in the insulin signaling pathway, with an IC50 value of 3.8 μM.

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