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Reticulol的可视化放大

Reticulol

A cAMP phosphodiesterase and DNA topoisomerase I inhibitor

原价
￥2037-16112
价格
￥ 1630-12890
Reticulol的二维码

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  • 库存: 现货
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  • 货号: ajci21744
  • CAS: 26246-41-3
  • 别名: 网状菌醇
  • 分子式: C11H10O5
  • 分子量: 222.2
  • 纯度: >98%
  • 溶解度: Soluble in DMSO
  • 储存: Store at -20°C
  • 库存: 现货

Background

Reticulol is an isocoumarin derivative produced by certain species of Streptomyces that inhibits cAMP phosphodiesterase (IC50 = 41 uM). It also inhibits DNA topoisomerase I when used at a concentration of 45 uM in B16F10 melanoma cells. Reticulol has antifungal activity against T. mentagrophyes with a MIC of 1.8 uM. It is cytotoxic against A427 human lung and B16F10 mouse melanoma cells at concentrations of 25 and 200 uM, respectively, and inhibits lung metastasis in mice.

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