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  3. Leukotriene A4 methyl ester
  • Leukotriene A4 methyl ester
Leukotriene A4 methyl ester的可视化放大

Leukotriene A4 methyl ester

A stable form of LTA4

原价
￥1737-27025
价格
￥ 1390-21620
Leukotriene A4 methyl ester的二维码

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  • 库存: 现货
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  • 货号: ajci21912
  • CAS: 73466-12-3
  • 别名: LTA4 methyl ester
  • 分子式: C21H32O3
  • 分子量: 332.5
  • 纯度: >98%
  • 溶解度: Acetone: >50 mg/ml,DMF: >50 mg/ml,DMSO: >50 mg/ml,Ethanol: >50 mg/ml,PBS pH 7.2: insoluble and unstable.
  • 储存: Store at -80°C; protect from light
  • 库存: 现货

Background

Leukotriene A4 (LTA4) is synthesized in mast cells, eosinophils, and neutrophils from arachidonic acid by 5-lipoxygenase (5-LO), which exhibits both lipoxygenase and LTA4 synthase activities. LTA4 is rapidly metabolized by LTA4 hydrolase or LTC4 synthase to LTB4 or LTC4, respectively. LTA4, from leukocytes, is known to undergo transcellular metabolism in platelets, erythrocytes, and endothelial cells. Further metabolism of LTA4 by 15-LO leads to lipoxin biosynthesis. LTA4 as a free acid is highly unstable. The methyl ester is stable and can be readily hydrolyzed to the free acid as needed.

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