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  • Gilvocarcin V
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Gilvocarcin V

An antitumor antibiotic

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Gilvocarcin V的二维码
  • 库存: 现货
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  • 包装
    价格
    促销价
    数量
  • 100ug
    ¥1437.00
    1150.00
    - +
  • 250ug
    ¥3025.00
    2420.00
    - +
  • 1mg
    ¥9100.00
    7280.00
    - +
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金额: ¥0.00
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  • 货号: ajci21922
  • CAS: 77879-90-4
  • 别名: 褐黄癌菌素V
  • 分子式: C27H26O9
  • 分子量: 494.5
  • 纯度: >98%
  • 溶解度: Soluble in DMSO
  • 储存: Store at -20°C
  • 库存: 现货

Background

Gilvocarcin V is an antitumor antibiotic with a coumarin-based aromatic structure that was orignally isolated from the culture broth of S. gilvotanareus. It is strongly active against Gram-positive bacteria such as S. aureus and B. subtilis and efficacious against experimental tumors including sarcoma 180, Ehrlich carcinoma, Meth I fibrosarcoma, MH134 hepatoma, and lymphocytic leukemia P388. Gilvocarcin V inhibits DNA synthesis by promoting the selective cross-linking of both histone H3 and the heat shock protein, GRP78 to DNA when photoactivated by near-UV or visible light.

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