现货大促销，价格低至8折起，量大更优惠，详细咨询客服
安捷凯生物医药，安捷凯化学
全部分类
全部分类
  1. 首页
  2. PKC (Protein kinase C)
  3. NPC-15437 (hydrochloride)
  • NPC-15437 (hydrochloride)
NPC-15437 (hydrochloride)的可视化放大

NPC-15437 (hydrochloride)

A selective PKC inhibitor

原价
￥625-4937
价格
￥ 500-3950
NPC-15437 (hydrochloride)的二维码

所有产品仅用于科学研究，我们不为任何个人用途提供产品和服务

询价有惊喜，量大更优惠 点击这里给我发消息

  • 库存: 现货
可选包装 >>>
首页
  • 货号: ajci22112
  • CAS: 141774-20-1
  • 别名:
  • 分子式: C25H50N4O2.2HCl
  • 分子量: 511.6
  • 纯度: >98%
  • 溶解度: DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 5 mg/ml,PBS (pH 7.2): 1 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

NPC-15437 is a selective protein kinase C (PKC) inhibitor (IC50 = 19 uM). It competitively inhibits phorbol ester- (Ki = 5 uM) and phosphatidylserine-induced (Ki = 12 uM) PKC activity but does not affect the activity of cAMP-dependent or Ca2+/calmodulin-dependent protein kinases. PKC signaling is involved in learning and memory, and when NPC-15437 was administered after Y maze training (0.1-10 mg/kg i.p.), it led to memory retention deficits in mice.

动态评分

0.0

没有评分数据
没有评价数据
一键回到顶部
展开 收缩
安捷凯在线客服