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Background:
AM694 is a potent synthetic cannabinoid (CB) with Ki values of 0.08 and 1.44 nM for the CB1 and CB2 receptors, respectively. AM694 4-iodo isomer is an analog of AM694 which contains a 4-iodophenyl group linked by methanone to the indole base. Its affinity for CB1 and CB2 receptors has not been determined. The pharmacological, physiological, and toxicological properties of AM694 4-iodo isomer are not known.
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