Mertansine

An anticancer agent

原价

￥450-4237

价格

￥ 360-3390

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库存: 现货

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产品引用

货号: ajci22730
CAS: 139504-50-0
别名: 美登素,DM1; Maytansinoid DM1
分子式: C35H48ClN3O10S
分子量: 738.29
纯度: >98%
溶解度: DMSO : ≥ 83.33 mg/mL (112.87 mM);Water : < 0.1 mg/mL (insoluble)
储存: Store at -20°C,unstable in solution, ready to use.
库存: 现货

Background

Mertansine (DM1) is a microtubulin inhibitor which binds at the tips of microtubules and suppresses the dynamicity of microtubules.. Mertansine is an antibody-conjugatable maytansinoid that was developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery.

参考文献:
[1]. Manu Lopus et al. Maytansine and Cellular Metabolites of Antibody-Maytansinoid Conjugates Strongly Suppress Microtubule Dynamics by Binding to Microtubules.

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Mertansine

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Background