Solcitinib

A JAK1 inhibitor

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库存: 现货

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包装

价格

促销价

数量
5mg

￥712.00

570.00

- +
10mg

￥962.00

770.00

- +
50mg

￥2725.00

2180.00

- +
100mg

￥3887.00

3110.00

- +
200mg

￥6212.00

4970.00

- +

已选 0 种 0 瓶

金额: ￥0.00

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Background

Solcitinib is an orally active, competitive, potent, selective JAK1 inhibitor, with an IC50 of 9.8 nM, and 11-, 55- and 23-fold selectivity over JAK2, JAK3 and TYK2, respectively; Solcitinib is used in the research of moderate-to-severe plaque-type psoriasis.

Solcitinib is an orally active, competitive, potent, selective JAK1 inhibitor, with an IC50 of 9.8 nM, and 11-, 55- and 23-fold selectivity over JAK2, JAK3 and TYK2, respectively. Solcitinib is used in the research of moderate-to-severe plaque-type psoriasis[1].

参考文献:
[1]. Ludbrook VJ, et al. Investigation of selective JAK1 inhibitor GSK2586184 for the treatment of psoriasis in a randomized placebo-controlled phase IIa study. Br J Dermatol. 2016 May;174(5):985-95.