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- HDAC (Histone deacetylases)
- Tinostamustine HCl
Tinostamustine HCl
An alkylatlng histone-deacetylase inhibitor (HDACi) fusion molecule
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包装价格促销价数量
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5mg￥3175.002540.00- +
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25mg￥11337.009070.00- +
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- 货号: ajci23186
- CAS: 1793059-58-1
- 别名: EDO-S101; EDO-S 101; EDO-S-101; EDO-S101 HCl; EDO-S101 hydrochloride; Tinostamustine hydrochloride
- 分子式: C19H29Cl3N4O2
- 分子量: 451.82
- 纯度: ＞98%
- 溶解度: Soluble in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
Tinostamustine, also known as EDO-S101, is an alkylatlng histone-deacetylase inhibitor (HDACi) fusion molecule. EDO-S101 is a functional pan-histone-deacetylase inhibitor and is assumed to potentiate the alkylating activity of the compound and/or may help to overcome resistance to other therapeutic agents.
Reference:
[1].? Mehrling T, Chen Y. The Alkylating-HDAC Inhibition Fusion Principle: Taking
[2]. Chemotherapy to the Next Level with the First in Class Molecule EDO-S101.
[3]. Anticancer Agents Med Chem. 2015;16(1):20-8. PubMed PMID: 25980817.
