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安捷凯生物医药，安捷凯化学
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  3. (±)17-HETE
  • (±)17-HETE
(±)17-HETE的可视化放大

(±)17-HETE

A potent inhibitor of proximal tubule ATPase activity

原价
￥2475-8875
价格
￥ 1980-7100
(±)17-HETE的二维码

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  • 库存: 现货
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  • 货号: ajci65112
  • CAS: 128914-47-6
  • 别名: (±)-Hydroxyeicosatetraenoic Acid
  • 分子式: C20H32O3
  • 分子量: 320.5
  • 纯度: >98%
  • 溶解度: 0.1 m Na2CO3: 2 mg/ml,DMF: Miscible,DMSO: Miscible,Ethanol: Miscible,PBS (pH 7.2): 0.8 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±)17-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney. At a concentration of 2 µM the (S)-enantiomer of 17-HETE inhibits proximal tubule ATPase activity by as much as 70%, whereas the (R)-isomer is inactive.

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