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  • Monactin
Monactin的可视化放大

Monactin

A non-selective monovalent cation ionophore

原价
¥4300-16025
价格
3440-12820
Monactin的二维码

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  • 库存: 现货
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  • 货号: ajci65468
  • CAS: 7182-54-9
  • 别名: 单活菌素
  • 分子式: C41H66O12
  • 分子量: 751
  • 纯度: >98%
  • 溶解度: DMF: Soluble,DMSO: Soluble,Ethanol: Soluble,Methanol: soluble
  • 储存: Store at -20°C
  • 库存: 现货

Background

Monactin is a mactrotetralide antibiotic originally isolated from Streptomyces and a non-selective ionophore for monovalent cations, including potassium, sodium, and lithium. It has low antimicrobial activity but is more active than its homolog nonactin . Monactin induces swelling of rat liver mitochondria in medium containing either potassium or sodium, stimulates respiration, and uncouples oxidative phosphorylation. It also inhibits Wnt signaling via inhibition of TCF-β-catenin transcriptional activity.

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