现货大促销,价格低至8折起,量大更优惠,详细咨询客服
全部分类
全部分类
  • Heat Shock Protein Inhibitor II
Heat Shock Protein Inhibitor II的可视化放大

Heat Shock Protein Inhibitor II

Prevents the synthesis of inducible heat shock proteins

原价
¥1550-6162
价格
1240-4930
Heat Shock Protein Inhibitor II的二维码

所有产品仅用于科学研究,我们不为任何个人用途提供产品和服务

询价有惊喜,量大更优惠 点击这里给我发消息

  • 库存: 现货
可选包装 >>>
首页
  • 货号: ajci65690
  • CAS: 1859-42-3
  • 别名: Hsp Inhibitor II, KNK 423
  • 分子式: C12H11NO3
  • 分子量: 217.2
  • 纯度: >98%
  • 溶解度: DMF: 10 mg/ml,DMSO: 10 mg/ml,DMSO:PBS (pH 7.2)(1:5): 0.1 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Heat shock protein (Hsp) inhibitor II is the active form of Hsp inhibitor I and a benzylidene lactam compound that prevents the synthesis of inducible Hsps, such as Hsp105, Hsp72, and Hsp40. Hsp inhibitor II decreases Hsp72 synthesis in vivo and reduces thermotolerance of tumors in SCC VII tumor-containing mice. At 100 µM, it inhibits the development of thermotolerance in COLO 320 DM cells. Inhibition of Hsp70 with Hsp inhibitor II in combination with amphotericin B increases susceptibility of AmB-susceptible (MICs = 0.058 versus 0.27 µg/ml for combined and AmB alone, respectively) and AmB-resistant (MICs = 21.33 versus >32 µg/ml for combined and AmB alone, respectively) strains of A. fumigatus.

动态评分

0.0

没有评分数据
没有评价数据
一键回到顶部
展开 收缩
安捷凯在线客服