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  • 3-hydroxy-3-Methylglutaric anhydride
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3-hydroxy-3-Methylglutaric anhydride

A precursor in the synthesis of HMG-CoA

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¥1212-5450
价格
970-4360
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  • 货号: ajci65840
  • CAS: 34695-32-4
  • 别名: 3-羟基-3-甲基戊二酸酐
  • 分子式: C6H8O4
  • 分子量: 144.1
  • 纯度: >98%
  • 溶解度: DMF: 10 mg/mL,DMSO: 10 mg/mL,Ethanol: 10 mg/mL,PBS (pH 7.2): 10 mg/mL
  • 储存: Store at -20°C
  • 库存: 现货

Background

The enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase mediates the rate-limiting step in cholesterol synthesis, converting HMG-CoA to mevalonate. 3-hydroxy-3-Methylglutaric anhydride is a precursor that is used in the synthesis of HMG-CoA. It has also been used in the synthesis of 3-alkyl-3-hydroxyglutaric acids that act as inhibitors of HMG-CoA reductase.

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