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  • JP104
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JP104

An irreversible FAAH inhibitor

原价
¥737-10350
价格
590-8280
JP104的二维码

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  • 货号: ajci65970
  • CAS: 887264-45-1
  • 别名: Click Tag JP104
  • 分子式: C25H30N2O3
  • 分子量: 406.5
  • 纯度: >98%
  • 溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:2): .25 mg/ml,Ethanol: 1 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

The enzyme, fatty acid amide hydrolase (FAAH), is widely expressed in brain and other tissues, and is capable of hydrolyzing anandamide (AEA) and other simple esters and amides with long unsaturated acyl chains. JP104 is an irreversible fatty acid amide hydrolase (FAAH) inhibitor of the carbamate class with an IC50 of 7.3 nM for the human recombinant enzyme when tested using radiolabeled oleamide as the substrate. The alkyl derivative on JP104 reacts with azide-modified reporter tags, such as azido-rhodamine or azido-biotin, for visualization of JP104 bound to FAAH in vivo.

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