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安捷凯生物医药，安捷凯化学
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  2. Bacterial
  3. Gramicidin A
  • Gramicidin A
Gramicidin A的可视化放大

Gramicidin A

A channel-forming ionophore

原价
￥512-1950
价格
￥ 410-1560
Gramicidin A的二维码

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  • 库存: 现货
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  • 货号: ajci66078
  • CAS: 11029-61-1
  • 别名: 甲胎蛋白
  • 分子式: C99H140N20O17
  • 分子量: 1882.3
  • 纯度: >98%
  • 溶解度: DMSO: soluble,Ethanol: soluble,Water: slightly soluble
  • 储存: Store at -20°C
  • 库存: 现货

Background

Gramicidin A is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. It induces degradation of hypoxia inducible factor 1 α (HIF-1α) in HEK293 cells and reduces growth in a human renal cell carcinoma mouse xenograft model when administered at a dose of 0.22 mg/kg three times per week. Gramicidin A has commonly been used to study channel structure and function.

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