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  • Pinostrobin
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Pinostrobin

A flavonoid with diverse biological activities

原价
¥562-4500
价格
450-3600
Pinostrobin的二维码

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  • 货号: ajci66238
  • CAS: 480-37-5
  • 别名: 球松素
  • 分子式: C16H14O4
  • 分子量: 270.3
  • 纯度: >98%
  • 溶解度: DMF: 20 mg/ml,DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml,DMSO: 12 mg/ml
  • 储存: 4°C, protect from light
  • 库存: 现货

Background

Pinostrobin is a flavonoid with diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties. It induces quinone reductase (QR) in murine hepatoma cells with a QR doubling concentration of 500 nM. Pinostrobin inhibits TNF-α and IL-1β production in RAW 264.7 macrophages (IC50s = 17.28 and 23.5 μM, respectively) and in LPS-stimulated rats (48.6 and 55% reduction, respectively). Pinostrobin also shows selective cytotoxicity for CCRF-CEM leukemia cells (IC50 = 10.2 μM) in a panel of eight cancer cell lines (IC50s = >30 μM).

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