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  • 14(S)-HDHA
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14(S)-HDHA

An anti-inflammatory lipid produced by macrophages

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14(S)-HDHA的二维码
  • 库存: 现货
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  • 25ug
    ¥1337.00
    1070.00
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  • 50ug
    ¥2562.00
    2050.00
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  • 100ug
    ¥4800.00
    3840.00
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  • 货号: ajci66654
  • CAS: 119433-37-3
  • 别名: 14(S)-HDoHE
  • 分子式: C22H32O3
  • 分子量: 344.5
  • 纯度: >98%
  • 溶解度: 0.1 M Na2CO3: 2 mg/ml,DMF: Miscible,DMSO: Miscible,Ethanol: Miscible,PBS (pH 7.2): 0.5 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Docosahexaenoic acid is a nutritionally-derived ω-3 fatty acid that is abundant in the brain and the retina and is thought to be important in early development and for therapeutic approaches to inflammatory disorders and cancer. 14(S)-HDHA is an oxygenation product of DHA that serves as a precursor to maresin 1 , an anti-inflammatory, pro-resolving mediator that prevents polymorphonuclear neutrophil (PMN) infiltration and stimulates macrophage phagocytosis. At doses as low as 0.2 ng/mouse 14(S)-HDHA administration resulted in reduced infiltration of PMNs into sites of inflammation.

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