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  2. Bacterial
  3. Reveromycin A
  • Reveromycin A
Reveromycin A的可视化放大

Reveromycin A

A spiroketal antibiotic with antiproliferative activity

原价
￥5787-11587
价格
￥ 4630-9270
Reveromycin A的二维码

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  • 库存: 现货
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  • 货号: ajci67174
  • CAS: 134615-37-5
  • 别名: 雷弗霉素A
  • 分子式: C36H52O11
  • 分子量: 660.8
  • 纯度: >98%
  • 溶解度: DMF: Soluble,DMSO: Soluble,Ethanol: Soluble,Methanol: Soluble
  • 储存: Store at -20°C
  • 库存: 现货

Background

Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp. It inhibits the mitogenic activity of epidermal growth factor in Balb/MK cells (IC50 = 0.7 µg/ml), displays antiproliferative activity against human KB and K562 tumor cell lines (IC50s = 1.9 and 1.6 µg/ml, respectively), and demonstrates antifungal activity against C. albicans (MIC = 2 µg/ml at pH 3). Reveromycin A also has been shown to inhibit bone resorption by inducing apoptosis in osteoclasts with an IC50 value of 0.7 µM.

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