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  • Reveromycin A
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Reveromycin A

A spiroketal antibiotic with antiproliferative activity

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Reveromycin A的二维码
  • 库存: 现货
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  • 包装
    价格
    促销价
    数量
  • 250ug
    ￥5787.00
    4630.00
    - +
  • 1mg
    ￥11587.00
    9270.00
    - +
已选 0 种 0 瓶
金额: ￥0.00
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使用我司产品发表的文章

  • 货号: ajci67174
  • CAS: 134615-37-5
  • 别名: 雷弗霉素A
  • 分子式: C36H52O11
  • 分子量: 660.8
  • 纯度: >98%
  • 溶解度: DMF: Soluble,DMSO: Soluble,Ethanol: Soluble,Methanol: Soluble
  • 储存: Store at -20°C
  • 库存: 现货

Background

Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp. It inhibits the mitogenic activity of epidermal growth factor in Balb/MK cells (IC50 = 0.7 µg/ml), displays antiproliferative activity against human KB and K562 tumor cell lines (IC50s = 1.9 and 1.6 µg/ml, respectively), and demonstrates antifungal activity against C. albicans (MIC = 2 µg/ml at pH 3). Reveromycin A also has been shown to inhibit bone resorption by inducing apoptosis in osteoclasts with an IC50 value of 0.7 µM.

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