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  2. HDAC (Histone deacetylases)
  3. HDAC3 Inhibitor
  • HDAC3 Inhibitor
HDAC3 Inhibitor的可视化放大

HDAC3 Inhibitor

An allosteric HDAC3 inhibitor

原价
￥800-6400
价格
￥ 640-5120
HDAC3 Inhibitor的二维码

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  • 库存: 现货
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  • 货号: ajci67232
  • CAS: 2044701-99-5
  • 别名: Histone Deacetylase 3
  • 分子式: C20H23N3O2
  • 分子量: 337.4
  • 纯度: >98%
  • 溶解度: DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 30 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

HDAC3 inhibitor is an allosteric inhibitor of histone deacetylase 3 (HDAC3; Ki = 0.16 nM). It is selective for HDAC3 over HDAC1 and HDAC2 (IC50s = 0.95, 11.81, and 95.45 nM, respectively, using recombinant HDACs). In addition, it is selective for acute myeloid, monocytic, and lymphoblastic leukemia cell lines (EC50s = 36.37, 76.64, and 151.7 nM, respectively) over chronic myeloid, acute promyelocytic, and acute lymphoblastic cells (EC50s = 2,160, >10,000, and >10,000 nM, respectively).

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