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  2. Cyclooxygenase (COX)
  3. 17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid
  • 17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid
17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid的可视化放大

17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid

A metabolite of DHA with anti-inflammatory properties

原价
￥800-6400
价格
￥ 640-5120
17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid的二维码

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  • 库存: 现货
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  • 货号: ajci67300
  • CAS: 1233715-28-0
  • 别名: EFOX, 17oxo4(Z),7(Z),10(Z),13(Z),15(E),19(Z)DHA, 17-oxo-DHA
  • 分子式: C22H30O3
  • 分子量: 342.5
  • 纯度: >98%
  • 溶解度: DMF: 15 mg/ml,DMSO: 10 mg/ml,Ethanol: 20 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DHA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPARγ agonist (EC50 = ~200 nM), and to inhibit pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 µM).

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