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Background:
JWH 250 is a synthetic cannabinoid (CB) which potently activates both CB1 and CB2 receptors (Ki values of 11 and 33 nM, respectively). It has been identified in herbal blends. JWH 250 N-(4-hydroxypentyl) metabolite is expected to be a cytochrome P450 phase I metabolite of JWH 250, detectable both in serum and urine.
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