(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (hydrobromide)

A dopamine receptor agonist

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库存: 现货

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5mg

￥650.00

520.00

- +
10mg

￥1225.00

980.00

- +
25mg

￥2975.00

2380.00

- +
50mg

￥5225.00

4180.00

- +

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货号: ajci67556
CAS: 13575-86-5
别名: (±)-ADTN, 6,7-ADTN, 6,7-diOHATN, NSC 287353
分子式: C10H13NO2?HBr
分子量: 260.1
纯度: >98%
溶解度: Water: 100mM
储存: Store at -20°C
库存: 现货

Background

(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (6,7-ADTN) is a dopamine receptor agonist (EC50s = 3.5 and 0.65 μM in rat striatal and nucleus accumbens homogenates, respectively). 6,7-ADTN stimulates production of cAMP in rat striatal homogenates, a process that is reduced by 70% in the presence of the dopamine antagonist fluphenazine at a concentration of 1 μM. In vivo, 6,7-ADTN induces hyperlocomotion in rats when injected bilaterally at a dose of 100 nmol per side into the nucleus accumbens. It increases cAMP production and glycoprotein secretion in the albumen gland of H. duryi (snail). It also reduces sucrose feeding in R. maderae (cockroach) nymphs.