(R)-Omeprazole (sodium salt)

An inactive isomer of a gastric proton pump inhibitor

原价

￥1337-10675

价格

￥ 1070-8540

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库存: 现货

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产品引用

货号: ajci67682
CAS: 161796-77-6
别名: 5-甲氧基-2-[(4-甲氧基-3,5-二甲基-2-吡啶基)-甲基]-3H-苯并咪唑钠盐
分子式: C17H19N3O3S?Na
分子量: 368.4
纯度: >98%
溶解度: DMF: 5 mg/ml,DMSO: 5 mg/ml,Ethanol: 1 mg/ml,PBS (pH 7.2): 5 mg/ml
储存: Store at -20°C
库存: 现货

Background

(R)-Omeprazole is the inactive isomer of omeprazole , a gastric proton-pump inhibitor. A stereoselective hydroxylation of (R)-omeprazole is mediated primarily by cytochrome P450 (CYP) 2C19, whereas CYP3A4 favors sulfoxidation of the active (S)-enantiomer . (R)-Omeprazole has been shown to act as a reversible direct-acting and metabolism-dependent inhibitor of CYP2C19 in pooled human liver microsomes (IC50 = 8.1 µM).

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生命科学

有机化学

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材料科学

(R)-Omeprazole (sodium salt)

(R)-Omeprazole (sodium salt)详情

Background