15(S)-HETE Ethanolamide

A CB1 receptor ligand and FAAH inhibitor

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25ug

￥2587.00

2070.00

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50ug

￥4875.00

3900.00

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100ug

￥9237.00

7390.00

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货号: ajci68092
CAS: 161744-53-2
别名: 15(S)-HAEA, 15(S)-Hydroxyeicosatetraenoic Acid Ethanolamide
分子式: C22H37NO3
分子量: 363.5
纯度: >98%
溶解度: DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 50 mg/ml,Ethanol:PBS (pH 7.2) (1:2): 5 mg/ml,PBS (pH 7.2): .1 mg/ml
储存: Store at -20°C
库存: 现货

Background

Arachidonoyl ethanolamide was the first endogenous cannabinoid (CB) to be isolated and characterized as an agonist acting on the same receptors (CB1 and CB2) as THC. Since that time, a number of related endocannabinoids have been isolated, most notably 2-arachidonoyl glycerol . Lipoxygenases, especially rabbit reticulocyte and soybean 15-lipoxygenases, actively convert endocannabinoids to their 15(S)-hydroperoxy and hydroxy metabolites. 15(S)-HETE ethanolamide is less potent than AEA at the CB1 receptor (Ki of 600 versus 90 nM). 15(S)-HETE ethanolamide also inhibits fatty acid amide hydrolase.