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  • 1-Oleoyl-2-acetyl-sn-glycerol
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1-Oleoyl-2-acetyl-sn-glycerol

A cell-permeable analog of DAG

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¥1150-9025
价格
920-7220
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  • 货号: ajci68266
  • CAS: 86390-77-4
  • 别名: 2-乙酰基-1-油酰基-SN-丙三醇,OAG
  • 分子式: C23H42O5
  • 分子量: 398.6
  • 纯度: >98%
  • 溶解度: 20 mg/ml in DMSO, 20 mg/ml in DMF, Miscible in Ethanol
  • 储存: Store at -80°C, protect from light
  • 库存: 现货

Background

OAG is a cell-permeable analog of the PKC-activating second messenger DAG. It activates PKC in platelets, resulting in the phosphorylation of a 40 kDa protein. OAG is metabolized to its corresponding phosphatidic acid (1-oleoyl-2-acetyl-3-phosphoglycerol), most likely through the action of a diglycerol kinase.[1]


Reference:
[1]. Nishizuka, Y. The role of protein kinase C in cell surface signal transduction and tumour promotion. Nature 308, 693-697 (1984).

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