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  • ADAMTS-5 Inhibitor
ADAMTS-5 Inhibitor的可视化放大

ADAMTS-5 Inhibitor

A disintegrin and metalloproteinase with thrombospondin motifs 5 inhibitor

原价
￥287-1900
价格
￥ 230-1520
ADAMTS-5 Inhibitor的二维码

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  • 库存: 现货
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  • 货号: ajci69686
  • CAS: 929634-33-3
  • 别名:
  • 分子式: C16H11ClF3N3OS3
  • 分子量: 449.9
  • 纯度: >98%
  • 溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml,Ethanol: 20 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) is an aggrecanase in that it cleaves aggrecan, a major proteoglycan in cartilage. While it has key roles in cartilage destruction associated with osteoarthritis, ADAMTS-5 is also involved in other pathways, including neurological processes. ADAMTS-5 Inhibitor is an inhibitor of ADAMTS-5 (aggrecanase-2; IC50 = 1.1 µM) with 40-fold selectivity over ADAMTS-4 (aggrecanase-1).

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