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A central cellular nucleotide
Adenosine 5'-monophosphate (AMP) is a central nucleotide with functions in metabolism and cell signaling. It is formed by the cleavage of ATP to yield AMP and inorganic pyrophosphate as well as from IMP in 2 steps catalyzed by adenylosuccinate synthase and adenylosuccinate lyase. AMP acts as an allosteric modulator of enzymes such as AMP-activated protein kinase (AMPK) and fructose-bisphosphate phosphatase.
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