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  2. Antifolate
  3. Aminopterin
  • Aminopterin
Aminopterin的可视化放大

Aminopterin

A synthetic folic acid derivative

原价
￥387-2362
价格
￥ 310-1890
Aminopterin的二维码

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  • 库存: 现货
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  • 货号: ajci69820
  • CAS: 54-62-6
  • 别名: 氨基蝶呤; 4-Aminofolic acid; APGA
  • 分子式: C19H20N8O5
  • 分子量: 440.4
  • 纯度: >98%
  • 溶解度: DMF: ,DMSO: ,Ethanol: Slightly,Water: Partly
  • 储存: Store at -20°C
  • 库存: 现货

Background

Aminopterin is a synthetic folic acid derivative whose metabolite is a competitive inhibitor of dihydrofolate reductase, which is a cofactor for nucleic acid synthesis. Aminopterin has anticancer and immunosuppressive properties. Formulations containing it have been used for pediatric leukemia though methotrexate is now more commonly used due to a more favorable therapeutic index. Aminopterin is a component of the widely used HAT (hypoxanthine-aminopterin-thymidine) medium to select cells for mammalian cell culture.

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