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- Antifolate
- Aminopterin
Aminopterin
A synthetic folic acid derivative
此产品仅用于科学研究，我们不为任何个人用途提供产品和服务
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包装价格促销价数量
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5mg￥387.00310.00- +
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10mg￥700.00560.00- +
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25mg￥1262.001010.00- +
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50mg￥2362.001890.00- +
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- 货号: ajci69820
- CAS: 54-62-6
- 别名: 氨基蝶呤; 4-Aminofolic acid; APGA
- 分子式: C19H20N8O5
- 分子量: 440.4
- 纯度: ＞98%
- 溶解度: DMF: ,DMSO: ,Ethanol: Slightly,Water: Partly
- 储存: Store at -20°C
- 库存: 现货
Background
Aminopterin is a synthetic folic acid derivative whose metabolite is a competitive inhibitor of dihydrofolate reductase, which is a cofactor for nucleic acid synthesis. Aminopterin has anticancer and immunosuppressive properties. Formulations containing it have been used for pediatric leukemia though methotrexate is now more commonly used due to a more favorable therapeutic index. Aminopterin is a component of the widely used HAT (hypoxanthine-aminopterin-thymidine) medium to select cells for mammalian cell culture.
