现货大促销,价格低至8折起,量大更优惠,详细咨询客服
全部分类
全部分类
  • bpV(phen) (potassium hydrate)
bpV(phen) (potassium hydrate)的可视化放大

bpV(phen) (potassium hydrate)

An inhibitor of phosphatases

原价
¥800-2400
价格
640-1920
bpV(phen) (potassium hydrate)的二维码

所有产品仅用于科学研究,我们不为任何个人用途提供产品和服务

询价有惊喜,量大更优惠 点击这里给我发消息

  • 库存: 现货
可选包装 >>>
首页
  • 货号: ajci70180
  • CAS: 171202-16-7
  • 别名: Bisperoxovanadium(phen), Potassium Bisperoxo(1,10phenanthroline) oxovanadate (V)
  • 分子式: C12H8N2O5V?K+(H2O)3
  • 分子量: 404.3
  • 纯度: >98%
  • 溶解度: DMSO: 1 mg/ml,PBS (pH 7.2): 10 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

bpV(phen) is a bisperoxovanadium (bpV) compound which inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 = 38 nM). It also inhibits the vascular endothelial PTP, PTP-β (IC50 = 343 nM), and PTP-1β (IC50 = 920 nM). At 0.1 mM, bpV(phen) inhibits SH2 domain-containing inositol 5'-phosphatase-2. Presumably by inhibiting insulin receptor kinase-associated PTPs, bpV(phen) activates the insulin receptor tyrosine kinase and promotes downstream signaling, including activation of PI3-kinase.

动态评分

0.0

没有评分数据
没有评价数据
一键回到顶部
展开 收缩
安捷凯在线客服