C10 Ceramide (d18:1/10:0)

A bioactive sphingolipid

原价

￥1425-2712

价格

￥ 1140-2170

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库存: 现货

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产品引用

货号: ajci70250
CAS: 111122-57-7
别名: N-癸酰-D-鞘胺醇,N-decanoyl-D-erythro-Sphingosine
分子式: C28H55NO3
分子量: 453.7
纯度: >98%
溶解度: 20mg/mL in DMSO, 22mg/mL in DMF, 33mg/mL in Ethanol
储存: Store at -20°C
库存: 现货

Background

C10 ceramide is an endogenous, bioactive sphingolipid produced by ceramide synthase. [1] C10 ceramide inhibits growth of wild-type and MDR1 gene-transfected MDA435/LCC6 human breast cancer cells with IC50 values of 44.1 and 46 μM, respectively. It also inhibits the growth of J774 murine macrophages in a dose-dependent manner.

Reference:
[1]. Shabbits, J.A., and Mayer, L.D. Intracellular delivery of ceramide lipids via liposomes enhances apoptosis in vitro. Biochim Biophys. Acta. 1612(1), 98-106 (2003).

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信号通路

生命科学

有机化学

无机化学

材料科学

C10 Ceramide (d18:1/10:0)

C10 Ceramide (d18:1/10:0)详情

Background