CAY10464

A potent, selective aryl hydrocarbon receptor antagonist

原价

￥350-2825

价格

￥ 280-2260

所有产品仅用于科学研究，我们不为任何个人用途提供产品和服务

询价有惊喜，量大更优惠

库存: 现货

可选包装 >>>

首页

产品引用

货号: ajci70560
CAS: 688348-37-0
别名:
分子式: C15H12Cl2O
分子量: 279.2
纯度: >98%
溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2)(1:1): .5 mg/ml,Ethanol: 10 mg/ml
储存: Store at -20°C
库存: 现货

Background

The aryl hydrocarbon receptor (AhR) is a ligand-dependent intracellular transcription factor whose ligands include some of the most infamous xenobiotics, including dioxin (TCDD, 2,3,7,8-tetrachlorodibenzoparadioxin), benzo[a]pyrene, and numerous polyaromatic hydrocarbons from soot particles and coal tar. CAY10464 is a potent and selective AhR antagonist, with a Ki of 1.4 nM when tested in rabbit liver cytosol preparations. It is inactive as an estrogen receptor ligands even at 100 µM.

动态评分

0.0

没有评分数据

没有评价数据

信号通路

生命科学

有机化学

无机化学

材料科学

CAY10464

CAY10464详情

Background