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CAY10512

A potent inhibitor of NF-κB

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CAY10512的二维码
  • 库存: 现货
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  • 包装
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    促销价
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  • 10mg
    ¥675.00
    540.00
    - +
  • 50mg
    ¥3087.00
    2470.00
    - +
  • 100mg
    ¥5412.00
    4330.00
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  • 500mg
    ¥25625.00
    20500.00
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已选 0 0
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  • 货号: ajci70572
  • CAS: 139141-12-1
  • 别名:
  • 分子式: C15H13FO
  • 分子量: 228.3
  • 纯度: >98%
  • 溶解度: DMF: 3 mg/ml,DMF:PBS (pH 7.2) (1:2): 0.3 mg/ml,DMSO: 2 mg/ml,Ethanol: 0.5 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

The nuclear factor-κB (NF-κB) regulates the expression of numerous genes involved in immunity and inflammation, cellular stress responses, growth, and apoptosis. Resveratrol, a polyphenolic trans-stilbene, is a known inhibitor of the activation of NF-κB and exhibits activity against a wide variety of cancer cells. CAY10512 is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity. The IC50 value for inhibition of TNFα-induced activation of NF-κB by CAY10512 is 0.15 µM compared to 20 µM by resveratrol.

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