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安捷凯生物医药，安捷凯化学
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  2. ROCK
  3. CAY10622
  • CAY10622
CAY10622的可视化放大

CAY10622

A ROCK1 and ROCK2 inhibitor

原价
￥1012-8050
价格
￥ 810-6440
CAY10622的二维码

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  • 库存: 现货
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  • 货号: ajci70610
  • CAS: 1038549-25-5
  • 别名:
  • 分子式: C25H25N5O3
  • 分子量: 443.5
  • 纯度: >98%
  • 溶解度: DMSO: 0.15 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Two Rho-associated kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The ROCKs play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, and stem cell renewal. CAY10622 is a potent, ureidobenzamide inhibitor of ROCK-I and ROCK-II kinases with IC50 values of 6 and 4 nM, respectively. It is inactive (showing greater then 100-fold selectivity) against an additional 44 kinases.

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