Ciprostene (calcium salt)
A stable analog of PGI2
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包装价格促销价数量
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1mg￥2562.002050.00- +
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5mg￥11450.009160.00- +
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10mg￥20175.0016140.00- +
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- 货号: ajci70782
- CAS: 81703-55-1
- 别名: Ciprostene calcium, U61431F
- 分子式: [C22H35O4]2?Ca2+
- 分子量: 767.1
- 纯度: ＞98%
- 溶解度: DMF: ＞ 25 mg/ml,DMSO: ＞ 16.8 mg/ml,ethanol: ＞ 34 mg/ml,PBS pH 7.2: ＞ 0.29 μ g/ml
- 储存: Store at -20°C
- 库存: 现货
Background
Ciprostene is the 9β-methyl analog of carbaprostacyclin and a stable analog of PGI2. Ciprostene exhibits biological activity similar to PGI2, but is 30-fold less potent. In patas monkeys, ciprostene induces hypotension and causes tachycardia when administered at a dose of 0.16 µg/kg/min. In addition, ciprostene inhibits ADP-induced platelet aggregation ex vivo and in vitro with ID50 values of 9.1 µg/kg/min and 60 ng/ml, respectively.
