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  3. Dabigatran Acyl-β-D-Glucuronide
  • Dabigatran Acyl-β-D-Glucuronide
Dabigatran Acyl-β-D-Glucuronide的可视化放大

Dabigatran Acyl-β-D-Glucuronide

A major active metabolite of dabigatran

原价
￥15237-15237
价格
￥ 12190-12190
Dabigatran Acyl-β-D-Glucuronide的二维码

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  • 库存: 现货
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  • 货号: ajci70984
  • CAS: 1015167-40-4
  • 别名: 达比加群酰基Β维葡糖苷酸
  • 分子式: C31H33N7O9
  • 分子量: 647.6
  • 纯度: >98%
  • 溶解度: Soluble in DMSO
  • 储存: Store at -20°C
  • 库存: 现货

Background

Dabigatran acyl-β-D-glucuronide is a major active metabolite of the thrombin inhibitor dabigatran . The prodrug of dabigatran, dabigatran etexilate , is hydrolyzed by plasma esterases to form dabigatran, which is metabolized primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT2B15 to form dabigatran acyl-β-D-glucuronide. Dabigatran acyl-β-D-glucuronide increases activated partial thromboplastin time (aPTT) in isolated human platelet-poor plasma equipotently to dabigatran.

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