GSK3 Inhibitor XIII

An inhibitor of GSK3

原价

￥962-5100

价格

￥ 770-4080

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库存: 现货

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产品引用

货号: ajci71822
CAS: 404828-08-6
别名: Glycogen Synthase Kinase 3 Inhibitor XIII
分子式: C18H19N5
分子量: 305.4
纯度: >98%
溶解度: DMF: 0.25 mg/ml,DMSO: 0.15 mg/ml
储存: Store at -20°C
库存: 现货

Background

GSK3 Inhibitor XIII is an aminopyrazole ATP-competitive inhibitor of glycogen synthase kinase 3 (GSK3), with 34% inhibition when used at a concentration of 2.5 µM. It inhibits androgen receptor transactivation in 22Rv1, LNCaP, and LNCaP-SSR cell lines in a dose-dependent manner. It promotes nuclear export of the androgen receptor and decreases translocation to the nucleus in PC3 and PCa prostate cancer cells, respectively. In HEK293 cells expressing the rat Nav1.2 channel, pretreatment with GSK3 inhibitor XIII dose-dependently potentiates peak current densities.

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生命科学

有机化学

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GSK3 Inhibitor XIII

GSK3 Inhibitor XIII详情

Background