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  • IBTP (iodide)
IBTP (iodide)的可视化放大

IBTP (iodide)

A mitochondria-targeting thiol reactive probe

原价
￥712-3625
价格
￥ 570-2900
IBTP (iodide)的二维码

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  • 库存: 现货
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  • 货号: ajci72016
  • CAS: 159085-21-9
  • 别名:
  • 分子式: C22H23IP?I
  • 分子量: 572.2
  • 纯度: >98%
  • 溶解度: Soluble in DMSO
  • 储存: Store at -20°C
  • 库存: 现货

Background

IBTP is a lipophilic cation that is accumulated in mitochondria and forms stable thioether adducts in a thiol-specific manner. As a result, mitochondrial proteins that have changed thiol redox state following oxidative stress are selectively tagged with IBTP and can be separated by two-dimensional electrophoresis and isolated. IBTP-tagged proteins can also be evaluated by immunoblotting using an antibody directed against the triphenylphosphonium moiety of the IBTP molecule. IBTP has also been used as a mitochondria-targeted soft electrophile to inhibit mitochondrial oxidative phosphorylation.

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