现货大促销，价格低至8折起，量大更优惠，详细咨询客服
安捷凯生物医药，安捷凯化学
全部分类
全部分类
  1. 首页
  2. Adrenergic Receptor
  3. JP-1302 (hydrochloride)
  • JP-1302 (hydrochloride)
JP-1302 (hydrochloride)的可视化放大

JP-1302 (hydrochloride)

An α2C-adrenergic receptor antagonist

原价
￥300-1625
价格
￥ 240-1300
JP-1302 (hydrochloride)的二维码

所有产品仅用于科学研究，我们不为任何个人用途提供产品和服务

询价有惊喜，量大更优惠 点击这里给我发消息

  • 库存: 现货
可选包装 >>>
首页
  • 货号: ajci72106
  • CAS: 1259314-65-2
  • 别名:
  • 分子式: C24H24N4?2HCl
  • 分子量: 441.4
  • 纯度: >98%
  • 溶解度: Soluble in DMSO
  • 储存: Store at -20°C
  • 库存: 现货

Background

JP-1302 is an antagonist of α2-adrenergic receptors (α2-ARs) that is selective for α2C-ARs over α2A- and α2B-ARs (Kis = 28, 3,150, and 1,470 nM, respectively). It reduces immobility time in the forced swim test in mice when administered at doses of 1, 3, and 10 µmol/kg. JP-1302 (5 mg/kg) reverses phencyclidine-induced decreases in prepulse inhibition of the acoustic startle response in rats. It dose-dependently reduces haloperidol-induced bradykinesia and catalepsy in mice. JP-1302 (0.3 mg/kg) also increases systolic blood pressure in rats.

动态评分

0.0

没有评分数据
没有评价数据
一键回到顶部
展开 收缩
安捷凯在线客服