Kukoamine B

A dual inhibitor of LPS and CpG DNA

原价

￥500-5600

价格

￥ 400-4480

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库存: 现货

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产品引用

货号: ajci72276
CAS: 164991-67-7
别名: 地骨皮乙素
分子式: C28H42N4O6
分子量: 530.7
纯度: >98%
溶解度: DMF: 30 mg/mL,DMSO: 30 mg/mL,Ethanol: 30 mg/mL,PBS (pH 7.2): 10 mg/mL
储存: Store at -20°C
库存: 现货

Background

Kukoamine B is a spermine alkaloid first isolated from a traditional Chinese herb L. chinense that inhibits both lipopolysaccharides (LPS) and oligodeoxynucleotides containing CpG motifs (CpG DNA). It is reported to inhibit proinflammatory signal transduction and cytokine expression induced by LPS and CpG DNA (Kds = 1.24 and 0.66 µM). LPS and CpG DNA are two well-recognized pathogen-associated molecular patterns (PAMPs) that play a role in triggering sepsis, thus sepsis may be attenuated by simultaneously neutralizing LPS and CpG DNA.

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生命科学

有机化学

无机化学

材料科学

Kukoamine B

Kukoamine B详情

Background