Metaproterenol (hemisulfate)

A long-acting β2-adrenergic receptor agonist

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库存: 现货

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25mg

￥362.00

290.00

- +
50mg

￥650.00

520.00

- +
100mg

￥1150.00

920.00

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货号: ajci72580
CAS: 5874-97-5
别名: 硫酸奥西那林,Orciprenaline hemisulfate
分子式: C11H17NO3?1/2H2SO4
分子量: 260.3
纯度: >98%
溶解度: DMSO: 1 mg/ml,PBS (pH 7.2): 10 mg/ml
储存: Store at -20°C
库存: 现货

Background

Metaproterenol is a β2-adrenergic receptor (β2-AR) agonist with bronchodilator actions. It inhibits TGF-α-induced hepatocyte DNA synthesis and proliferation in vitro (IC50 = 15 nM), an effect that is reversed by the β2-AR antagonist butoxamine but not the β1-AR antagonist metoprolol . Metaproterenol dose-dependently relaxes lung strips and increases heart rate and inotropy of right atria and left atria, respectively, isolated from guinea pig (pD2s = 6.4, 7.08, and 6.61, respectively). Formulations containing metaproterenol were previously used as long-acting bronchodilators for the treatment of asthma.