N-Desethylamiodarone (hydrochloride)

A CYP3A4 metabolite of amiodarone

原价

￥1212-19487

价格

￥ 970-15590

N-Desethylamiodarone (hydrochloride)的二维码

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库存: 现货

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产品引用

货号: ajci72934
CAS: 96027-74-6
别名: 去乙基胺碘酮,N-desethylamiodarone hydrochloride; LB 33020 hydrochloride
分子式: C23H25I2NO3?HCl
分子量: 653.7
纯度: >98%
溶解度: DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 5 mg/ml
储存: Store at -20°C
库存: 现货

Background

Amiodarone is a class III antiarrhythmic agent, in that it prolongs both cardiac action potential and refractoriness by blocking potassium currents. It inhibits the voltage-gated potassium channel hERG, also known as KCNH2, with an IC50 value of 1 µM. In humans, cytochrome P450 3A is involved in the metabolism of amiodarone. N-Desethylamiodarone is the major, active metabolite of amiodarone. This compound has been used as an analytical reference standard for quantifying amiodarone in plasma samples.

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生命科学

有机化学

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材料科学

N-Desethylamiodarone (hydrochloride)

N-Desethylamiodarone (hydrochloride)详情

Background