NF-κB Control
A negative control peptide used with NF-κB inhibitor
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包装价格促销价数量
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500ug￥1550.001240.00- +
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1mg￥2800.002240.00- +
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5mg￥10787.008630.00- +
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- 货号: ajci73018
- CAS: 201608-17-5
- 别名: SN50M
- 分子式: C123H215N33O30S
- 分子量: 2668.3
- 纯度: ＞98%
- 溶解度: DMF: 25 mg/ml,DMSO: 10 mg/ml,Ethanol: 1 mg/ml,PBS (pH 7.2): 1 mg/ml
- 储存: Store at -20°C
- 库存: 现货
Background
NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. It blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α. NF-κB control is a peptide that is identical in sequence to NF-κB inhibitor, except two essential, basic residues of the p105 NLS are substituted with non-basic amino acids. It is ineffective at blocking the activation of NF-κB signaling and is used as a negative control peptide.
