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  • Oleoyl Oxazolopyridine
Oleoyl Oxazolopyridine的可视化放大

Oleoyl Oxazolopyridine

A potent FAAH inhibitor

原价
¥575-19925
价格
460-15940
Oleoyl Oxazolopyridine的二维码

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  • 货号: ajci73244
  • CAS: 288862-58-8
  • 别名: CAY10400
  • 分子式: C24H36N2O2
  • 分子量: 384.6
  • 纯度: >98%
  • 溶解度: DMF: 10 mg/ml,DMSO: 10 mg/ml,DMSO:PBS (pH 7.2) (1:2): .05 mg/ml,Ethanol: 10 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide. Oleoyl oxazolopyridine is a potent inhibitor of FAAH exhibiting Ki values of 1.3 and 2.3 nM for the human and rat enzymes, respectively. Oleoyl oxazolopyridine is approximately 35-fold more potent than oleyl trifluoromethyl ketone when assayed under the same conditions. Selectivity of oleoyl oxazolopyridine for FAAH versus cannabinoid receptors or PLA2 has not been reported.

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