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  2. Adrenergic Receptor
  3. Olodaterol
  • Olodaterol
Olodaterol的可视化放大

Olodaterol

A selective β2-AR agonist

原价
￥537-7775
价格
￥ 430-6220
Olodaterol的二维码

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  • 库存: 现货
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  • 货号: ajci73258
  • CAS: 868049-49-4
  • 别名: 奥达特罗,BI1744
  • 分子式: C21H26N2O5
  • 分子量: 386.4
  • 纯度: >98%
  • 溶解度: DMF: 20 mg/ml,DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml,DMSO: 15 mg/ml,Ethanol: 1 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Olodaterol is a selective agonist of β2-adrenergic receptors (β2-ARs; EC50s = 97.7 and 2,725 nM for human β2- and β1-ARs, respectively). In vivo, olodaterol completely reverses acetylcholine-induced bronchoconstriction without cardiovascular side effects in guinea pigs. It also exhibits dose-dependent bronchoprotection in a beagle model of acetylcholine-induced bronchoconstriction for a period of 24 hours, indicating potential for once-daily dosing. Formulations containing olodaterol have been used to treat bronchoconstriction associated with chronic obstructive pulmonary disease.

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